CORDIS Project
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This project investigates the self-organization of liver tissue to understand its structure and function. It aims to create a digital model of liver architecture and explore the molecular mechanisms that govern cell organization, with the goal of reengineering liver tissue.
We want to understand the rules of self-organization underlying tissue structure and function.
To address this problem, we have chosen the mouse liver with its complex apico-basal polarity of hepatocytes and its unique 3D tissue organization.
We aim at identifying the rules of self-organization of liver tissue and their implementation at the molecular level.
Our ultimate goal is to demonstrate that it is possible to reengineer liver tissue structure.
The first aim will be to develop a digital ge…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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