CORDIS Project
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This project aims to investigate the role of S-palmitoylation in regulating receptor tyrosine kinases in breast cancer. By developing innovative chemical biological tools, it seeks to uncover new therapeutic strategies targeting these receptors to improve treatment outcomes for patients.
Breast cancer is one of the most diagnosed cancers and the leading cause of cancer death in women worldwide.
Breast cancer cells need activated receptor tyrosine kinases (RTKs) to invade, proliferate, and metastasize.
Increased activity and overexpression of RTKs is associated with poor prognosis for breast cancer patients.
Therefore, multiple RTKs have emerged as attractive therapeutic targets.
However, resistance to therapies is a persistent problem for the development of therapeutics targetin…
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