CORDIS Project
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The project investigates the use of reversible self-assembled monolayers as dynamic nanoparticle shells to enhance drug delivery and virus detection. By enabling multivalent interactions, these systems aim to improve the effectiveness of antiviral treatments and develop sensitive virus sensors.
This proposal concerns Reversible Self-assembled Monolayers (rSAMs) as dynamic nanoparticle shells for multivalent interactions at biointerfaces.
Current drug design and diagnostics are exploring the multivalency concept, i.e. binding of biological targets via multiple weak interactions.
In contrast to classical drug design relying on high-affinity inhibitors, thisrelies on dendritic architectures featuring a high density of ligands, e.g. saccharides, capable of simultaneously interacting with b…
MALMO UNIVERSITET
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