CORDIS Project
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This project investigates the role of the Polycomb Repressive Complex 2 in plant development, specifically how it regulates light acclimation in fully differentiated cells of Arabidopsis thaliana. By utilizing molecular profiling techniques, the project aims to uncover the mechanisms of epigenetic gene repression and i…
Polycomb Repressive Complex 2 (PRC2) is an evolutionarily conserved histone methyltransferase complex that catalyses trimethylation of lysine 27 of histone H3 (H3K27me3), which leads to epigenetic gene repression.
In Arabidopsis thaliana (A. thaliana), CURLY LEAF (CLF) and SWINGER (SWN) are two major H3K27 methyltransferases and core components of PRC2 in the sporophyte, playing essential roles in the regulation of plant development.
However, the knowledge of how PRC2 participates in operational…
BIOLOGICKE CENTRUM AKADEMIE VID CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE
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