CORDIS Project
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This research investigates the role of glycosylation in resistance to HER2-targeted therapies in breast cancer. It aims to identify genetic factors affecting treatment response and explore new therapeutic options.
Resistance and cancer progression remain a major obstacle to the successful treatment of cancer.
In HER2+ breast cancer, the development of targeted therapies such as trastuzumab, has revolutionized the treatment for these cancer patients.
However, a significant number of patients develop resistance.
In this realm, my previous work focused on understanding the crosstalk of interconnected signaling pathways in HER2+ cancer cells that drive tumorigenesis and undermine the efficacy of current treat…
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
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