CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project focuses on identifying genomic cis-regulatory modules (CRMs) that control gene expression, particularly in neurons affected by mutations in the MeCP2 gene linked to Rett Syndrome. A novel method called FIREWACh will be used to quantify CRM activity, providing insights into gene regulation and cognitive beh…
Precise regulation of gene expression is achieved through the coordinated action of genomic cis-regulatory modules (CRMs).
The identification of CRMs has long been a goal of functional genomics as CRM dysregulation can have devastating consequences for health and development such as autism.
For example, mutations in the MeCP2 gene, which encodes protein that binds methylated DNA and regulates gene expression in neurons, results an Autism Spectrum Disorder termed Rett Syndrome.
While thought to m…
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
