CORDIS Project
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This project investigates the role of mitochondria in cardiomyopathies, a common genetic disorder. It aims to understand the signaling pathways involved in the disease, focusing on the impact of reactive oxygen species and mitochondrial function.
Mitochondrial diseases are now considered to be among the most common forms of genetic disorders, with a minimum prevalence of 1 in 5000 individuals.
They can be caused by mutations in either the nuclear or the mitochondrial DNA (mtDNA).
One of the most well characterized clinical presentations is neuromuscular dysfunction, followed by cardiomyopathy, generally in the form of hypertrophic cardiomyopathy.
Nowadays there are several clinical treatments approved for mitochondrial diseases.
However…
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
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