CORDIS Project
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This project investigates the behavior of adult stem cells in skeletal muscle, focusing on satellite cells that activate during tissue repair. By analyzing specific genes, the research aims to uncover new regulators of muscle regeneration and improve understanding of stem cell activation and quiescence.
Stem cells are present in many adult tissues in a quiescent state.
Their contribution to tissue repair depends on their activation, leading to proliferation and subsequent differentiation or return to quiescence.
Skeletal muscle provides a model in which to study adult stem cell behavior.
This tissue regenerates after injury and the muscle satellite cell is key to this process.
These quiescent cells, located under the basal lamina of muscle fibres become activated upon injury, proliferate and di…
INSTITUT PASTEUR
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