CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of specific isoforms of phosphoinositide 3-kinases in cell transformation and their associated signaling mechanisms. It aims to understand how these isoforms contribute to therapeutic resistance in diseases like cancer, using advanced gene-targeted mouse models and a novel phosphoprot…
PI 3-kinases (PI3Ks) generate intracellular lipid second messengers that regulate many cellular processes including cell survival, proliferation, migration and differentiation.
The PI3K signalling pathway has been implicated in diseases such as cancer, inflammation and diabetes, and PI3Ks are therefore considered as attractive new therapeutic targets in the pharmaceutical and biotech industry.
Mammals have 8 isoforms of PI3K, and therapeutic interference with PI3K signalling may have to be targe…
QUEEN MARY UNIVERSITY OF LONDON
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
