CORDIS Project
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This research explores the role of the exosporium in the survival and resistance of bacterial spores, particularly in Bacillus species. It aims to understand how this structure contributes to environmental resilience and immune evasion, potentially informing therapeutic strategies.
The exosporium is not unique to Bacillus anthracis and is present in all members of the B.cereus group and some clostridia.
The function this complex structure plays in the survival of these spores is as yet unknown.
One possibility is that it acts as a physical barrier passively reacting with biocides before they have the chance to reach essential molecules located within the spore core.
We propose to determine the contribution the exosporium makes to environmental survival and bioc…
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