CORDIS Project
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This project investigates the role of the locus coeruleus and its modulation by specific receptors in neuropathic pain, a chronic condition that is resistant to standard pain relief methods. By exploring the physiological mechanisms involved, the research aims to inform the development of new treatments targeting this…
The locus coeruleus, the main source of noradrenaline in the central nervous system, is a crucial step in both the descending and ascending pain modulatory systems which are compromised in neuropathic pain.
Neuropathic pain is a chronic pathological condition arising from damage in the nervous system and that does not respond successfully to conventional analgesics.
In fact, the first-line treatment approaches for neuropathic pain belong to drugs that modulate the activity of the locus coeruleus…
UNIVERSIDAD DE CADIZ
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