CORDIS Project
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This project investigates the role of micro-RNA molecules in T cell development and allergic inflammation. By creating a novel animal model, it aims to uncover how these regulatory molecules influence immune responses, potentially leading to new therapeutic targets for allergies.
It is estimated that more than 200 million Europeans suffer from at least one type of allergy.
This condition is elicited by an hyper-activated type-2 inflammatory response coordinated by T helper (TH)-2 cells.
In spite a good insight into the molecular mechanisms that triggers TH2 cells activation, the lack in understanding their post-transcriptional regulation is hampering the access to new potential therapeutic targets to curtail the allergy epidemic.Micro-RNA (miRNAs) are regulatory molecule…
THE FRANCIS CRICK INSTITUTE LIMITED
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