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RODIN develops innovative biomaterial units that enable stem cells to autonomously shape their environments. By integrating synthetic biology and computer modeling, the project aims to create tailored microenvironments for targeted cell differentiation, with applications in regenerative medicine and disease modeling.
Geometrical, mechanical, and biochemical signals are master regulators of differentiation and other cellular processes.
Biomaterials have been used to create artificial 3D niches recapitulating such favourable cues, traditionally optimized through progressive and laborious design-build-test-learn cycles.
In native environments, however, cells dynamically interact and modify their surroundings, engaging in feedback loops that alter their phenotype and trigger collective effects.
Based on such pri…
UNIVERSIDADE DE AVEIRO
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IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom, LONDON
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Portugal, Lisboa
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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