CORDIS Project
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This project investigates the role of the BANK1 protein in B cell activation related to Systemic Lupus Erythematosus, an autoimmune disease. By studying its signaling pathways in a mouse model, the research aims to uncover mechanisms that contribute to B cell hyperactivation and potential therapeutic targets.
Systemic Lupus Erythematosus (SLE, Lupus) is a life-threatening and incurable autoimmune disease that affects primarily women, its pathogenesis is related with an exaggerated B cells activation that results both in the generation of antibodies against self-nuclear acid antigens and in the generation of subsets of B cells that can exert antibody-independent roles in Lupus.
However, the mechanisms that regulate aberrant B cell functions are poorly understood.
In this project, we propose to investi…
FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD M.P.
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