CORDIS Project
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This project explores the location and movement of RNA degradation machinery in Escherichia coli. It aims to understand how environmental stresses affect the positioning and dynamics of RNA degradation enzymes, potentially linking their cellular location to RNA decay processes.
The aim of this research proposal is to investigate in detail the location and mobility of RNA degradation machinery in E. coli. RNA decay has been widely studied in bacteria but continues to reveal subtle secrets [1,2].
Recent research demonstrates that the degradosome complex forms cytoskeletal-like structures linked with the inner cell membrane [3].
Preliminary results from Cecilia Arraiano’s laboratory (host laboratory) have shown that RNase R colocalises with the bacterial nucleoid, whereas…
INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA
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