CORDIS Project
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This project focuses on identifying RNA-binding proteins that regulate mRNA interactions, particularly in human adrenal cells. By creating a comprehensive regulatory map, the research aims to enhance understanding of post-transcriptional regulation and its implications for hormone production.
RNA-binding proteins (RBPs) regulate the processing and expression of protein-coding transcripts.
The goal of the proposed research is to develop a strategy to determine specific mRNA regulatory factors and elements important for investigating any biological processes.
First, we will construct a transcriptome-wide post-transcriptional regulatory map of RBP-mRNA interactions by probabilistic modeling of protein occupancy profiles and RNA sequence data, simultaneously inferring binding locations o…
MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
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