CORDIS Project
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The project investigates RNA modifications in the Rn7sk non-coding RNA and their influence on neuronal cell fate and brain development. By employing advanced techniques, the research aims to uncover how these modifications regulate essential cellular processes.
The Epitranscriptome is the assembly of over 170 chemical RNA modifications that play fundamental roles in the majority of cellular processes. RNA modifying enzymes and proper control of neuronal cell fate are essential for brain development and dysfunction in any of these processes results in severe neurodevelopmental disorders.
To date, the role of non-coding RNAs (ncRNAs) as key regulators of sophisticated molecular pathways is becoming increasingly clear. A key regulatory ncRNA that modulate…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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