CORDIS Project
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This project investigates the role of long non-coding RNAs and their associated proteins in neuronal differentiation and neurodegenerative diseases. It aims to uncover how these RNA molecules interact with proteins to regulate cellular pathways and prevent toxic aggregates.
A major portion of the eukaryotic genome is occupied by DNA sequences whose transcripts do not code for proteins.
This part of the genome is transcribed in a developmentally regulated manner and in response to external stimuli to produce large numbers of long non-coding RNAs (lncRNAs).
From the beginning of transcription through splicing and translation, RNA molecules are associated with numerous RNA binding proteins that regulate their processing, stability, transport and translation.
Both codi…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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