CORDIS Project
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This project seeks to recreate a living model of the Last Universal Common Ancestor by engineering bacterial hybrids that utilize RNA for genetic information. It combines innovative techniques to explore the transition from an ancient RNA world to modern DNA-based life.
Modern cellular life strictly depends on DNA as genetic material.
However, a large body of evidence infers the existence of a previous, more primitive biology in which RNA also stored information in cellular entities.
Recreating a living cellular fossil representing this transition from an ancient RNA world to modern DNA-based life would fundamentally advance our understanding of our biology’s history, and enable us to explore its biological properties experimentally.
However, the reengineering…
TECHNISCHE UNIVERSITAT DORTMUND
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