CORDIS Project
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This project investigates the regulatory mechanisms of inflammation, focusing on the role of ribosomes and mRNA translation in controlling inflammatory responses. By understanding these processes, the project aims to identify new therapeutic targets for treating inflammatory disorders.
Inflammation is a highly regulated process that acts as a first line of defense against pathogens infections.
Triggered by cellular pattern recognition receptors (PRRs) that recognize specific microbial components and endogenous or exogenous non-microbial components, activation of inflammation induces a dynamic and coordinated gene expression program that leads to the production of cytokines and chemokines to attract effector cells to the site of infection.
Although a robust inflammatory respons…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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