CORDIS Project
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This research focuses on the role of specialized ribosomes in cancer metastasis, exploring how variations in ribosomal composition can influence gene expression and disease progression. The goal is to identify potential biomarkers and therapeutic targets related to ribosomal functions in cancer.
Protein translation, considered a mere reflection of transcription, emerges as a regulatory hub, shaping proteomes and directing cellular outcomes.
This is due to existence of heterogeneous ribosome populations, yielding specialized ribosomes that drive context-dependent translation.
While technological advances enable mapping of ribosomal diversity, questions remain as to the prevalence of the phenomenon and the mechanisms by which specialized ribosomes confer specific functions.
Studies propos…
TEL AVIV UNIVERSITY
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