CORDIS Project
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This project focuses on understanding a specific glycosylation pathway in mammalian cells that is crucial for health. By developing new chemical tools, it aims to investigate the role of unique carbohydrates in disease and normal cellular function.
Cell-surface proteins are decorated with a variety of different carbohydrate structures that play central roles in mammalian biology.
The complex nature of glycan structures and the pathways by which they are assembled make it a challenging task to decipher their exact function in cells, knowledge that is essential if we are to understand how malfunctioning leads to disease.
This proposal aims to deliver innovative approaches to probe a distinct pathway of glycosylation essential to mammalian bi…
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