CORDIS Project
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This project investigates the role of the RET receptor tyrosine kinase in cell movement and cancer progression. By using light-activated inhibitors, researchers aim to control RET activity and study its trafficking dynamics, providing insights into its involvement in tumor invasion and potential therapeutic targets.
Protein kinases play a critical role in a number of cellular processes, including cell proliferation, differentiation and apoptosis.
The REarranged during Transfection (RET) receptor tyrosine kinase plays important roles in regulating cellular proliferation, migration, and survival in the normal development of neural crest derived tissues.
Furthermore, aberrant activation of RET, through oncogenic mutations or overexpression, can contribute to tumourigenesis, regional invasion, and metastasis of…
UGOT - GOETEBORGS UNIVERSITET/UNIVERSITY OF GOTHENBURG
GOETEBORGS UNIVERSITET
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