CORDIS Project
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This project investigates the role of prostaglandin E2 in neuromuscular junction integrity and its potential as a treatment for sarcopenia, a condition characterized by muscle loss in aging. By inhibiting an enzyme that degrades prostaglandin E2, the project aims to restore muscle function and improve mobility in aged…
Aging is characterised by a progressive decline in muscle mass and force, potentially resulting in the insurgence of sarcopenia.
Sarcopenic patients are at an increased risk of falls and fractures, with a concordant decrease in mobility and personal independence.
Evidence suggests that key determinants of sarcopenia insurgence are muscle denervation, failure of its reinnervation and degeneration of neuromuscular junctions (NMJ), representing the connection between the nerve and the muscle and es…
UNIVERSITA DEGLI STUDI DI PADOVA
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United States, Stanford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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