CORDIS Project
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The project investigates the assembly mechanisms of bacterial respiratory Complex I and its interactions with stress response proteins. It employs advanced biophysical methods to understand protein folding and its implications for antibiotic resistance.
Cellular respiratory complexes play a central role in the production of ATP, the universal energy source of life.
Defects in their activity are linked to neurodegenerative diseases in humans and antibiotics resistance in bacteria.
Despite their capital importance, the assembly mechanisms of respiratory complexes remain highly unexplored.This research project aims to investigate how the assembly of the major bacterial respiratory Complex I is assisted by a multi protein system involved in enterob…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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