CORDIS Project
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The ResilMS project investigates the molecular profiles of oligodendrocytes in multiple sclerosis to understand their resilience during disease progression. By using advanced genetic techniques, it aims to identify genetic factors that influence remyelination and may lead to improved diagnostics and therapies for MS.
Multiple sclerosis (MS) is a prevalent demyelinating disease that primarily affects young adults.
Current therapy for MS mainly focuses on immune suppression and alleviating inflammation.
However, efforts to promote remyelination face challenges in clinical translation.
Animal models of acute demyelination have demonstrated promising remyelination, primarily facilitated by newly generated oligodendrocytes.
Nevertheless, the scenario in human MS differs, as the disease typically manifests in adul…
KAROLINSKA INSTITUTET
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