CORDIS Project
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This project investigates the regenerative potential of adult parietal epithelial multipotent progenitors (APEMP) found in human kidneys. By studying their role in kidney repair, the project aims to develop new therapies for chronic kidney disease and understand the mechanisms behind kidney cell regeneration.
Chronic Kidney Disease (CKD) affects 11% of the adult population and is considered by the WHO as one of the health emergencies of the 21st century.
Although cell therapy might be beneficial for CKD, human stem cells that might be used to improve kidney function were so far unknown.
Recently, we demonstrated the existence of resident stem cells in the urinary pole of the Bowman’s capsule of adult human kidney and therefore named as adult parietal epithelial multipotent progenitors (APEMP).
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UNIVERSITA DEGLI STUDI DI FIRENZE
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