CORDIS Project
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This project develops a technology to efficiently produce human brain organoids from patients, enabling the study of neurodevelopmental diseases like Fragile X Syndrome. By utilizing advanced stem cell techniques, it aims to uncover genetic and epigenetic factors influencing brain development and explore potential ther…
Understanding the neurodevelopmental causes and mechanisms of the brain disease is challenging due to the limited access to the human brain tissues, the complexity of brain anatomy and the lack of accurate models to recapitulate human brain development.
The convergence between induced pluripotent stem cell and organoid technology enable to recapitulate key features of early human neurodevelopment disease in vitro.
However, the low efficiency, high cost and technical variability of generating ind…
UNIVERSITA DEGLI STUDI DI PADOVA
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