CORDIS Project
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This project investigates the role of intestinal resident CD8+ T lymphocytes in response to viral infections and their impact on gut health. It aims to understand how these immune cells adapt to various challenges, such as inflammation and diet, which could inform new diagnostic and therapeutic strategies for intestina…
Intestinal epithelial resident CD8+ T lymphocytes, such as intraepithelial lymphocytes (IELs), are located at epithelial barriers.
They play a key role in tissue protection by promoting the elimination of infected cells, while producing antimicrobial factors and epithelial growth factor.
Due to the positioning of IELs underneath the single epithelial layer and their potential involvement in modulating intestinal pathology, the activation status of IELs is intensively studied.
Viruses modify CD8…
SVEUCILISTE U RIJECI, MEDICINSKI FAKULTET
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