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REPRO-PTP focuses on developing targeted therapies for liver cancer associated with obesity. By inhibiting specific proteins that drive cancer progression, the project aims to improve treatment outcomes and survival rates for patients suffering from this aggressive form of cancer.
REPRO-PTP is addressing the critical need for effective treatments in obesity-associated hepatocellular carcinoma (HCC). HCC, which accounts for 90% of primary liver cancers, is refractory to conventional chemotherapy with very low survival rate.
As obesity is a major risk factor for HCC, it is imperative to develop new therapeutic approaches.
My laboratory has identified receptor protein tyrosine phosphatases (PTPs) as key regulators of glycolysis and lipogenesis, with PTPRK emerging as a parti…
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