CORDIS Project
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This project investigates the evolution of antimicrobial resistance in bacteria, focusing on the role of evolutionary forces like history and selection. It aims to understand how plasmids contribute to the spread of resistance, particularly in Klebsiella pneumoniae.
Antimicrobial resistance (AMR) in bacteria is one of the main challenges faced by modern medicine and understanding its evolution is urgently required.
As any other evolved trait, three fundamental evolutionary forces guide the evolution of AMR: history, chance and selection.
The specific role of each force determines whether, by what mechanism, and to what degree AMR evolves in a given population.
Horizontal gene transfer is the main route for acquisition of AMR in bacterial pathogens and plas…
FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO RAMON Y CAJAL
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