CORDIS Project
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The RePLASTIC project aims to identify novel regulators that influence the plasticity and identity of cells during reprogramming. By utilizing gene editing techniques and next-generation sequencing, the project seeks to enhance our understanding of cellular conversion processes, with potential applications in immunothe…
Cellular reprogramming has revolutionized stem cell biology by allowing the generation of stem cells, progenitors, or somatic cell identities with small combinations of transcription factors (TFs).
Currently, the limited understanding of how these different degrees of plasticity are established and maintained keeps on hold the application of reprogrammed cells in the clinic.
With the RePLASTIC project, I propose to uncover novel regulators that define degrees of plasticity and control cell ident…
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