CORDIS Project
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This project focuses on developing innovative gene therapy vectors to address inherited kidney diseases, particularly Autosomal Dominant Polycystic Kidney Disease. By utilizing advanced gene editing technologies, the aim is to create effective treatments that can correct genetic defects in kidney cells.
Chronic kidney disease (CKD) is a leading cause of global mortality, affecting ~13% of global population.
Inherited kidney diseases (IKD) are estimated to account for a 30% of CKD cases.
Despite the unprecedented development of genetic medicines in the past decades, to date no kidney gene therapy intervention is available.
Renal gene therapies have encountered two main barriers: (1) its complex anatomy and function has hampered efficient and specific delivery of genetic therapies to the kidney,…
FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
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