CORDIS Project
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This research examines the role of microexons in regulating the specificity of kinases within signaling networks. By investigating the impact of these microexons on kinase interactions and their potential dysregulation in cancer, the project aims to enhance understanding of cellular signaling variations across differen…
Signaling networks control a vast range of complex cellular behaviors.
The wiring of these networks varies greatly from one cell type to another in the body, depending on the specific functions required of different tissues.
However, the mechanisms controlling the tissue-specific wiring of signaling networks are poorly understood.
Kinases play a major role in directing signal flow by interacting with and phosphorylating specific target proteins.
Interestingly, recent studies on the tissue-specif…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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