CORDIS Project
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This project investigates the concept of trained immunity in respiratory epithelial cells, exploring how these cells adapt after initial infections. Using advanced laboratory models, it aims to uncover the metabolic and genetic changes that enhance immune responses, potentially leading to new treatments for respiratory…
Immunological memory, once thought to be exclusive to the adaptive immune system, is now increasingly recognized as a feature of innate immunity.
This phenomenon, known as trained immunity, enables innate immune cells to undergo lasting functional changes after an initial infection, improving their response to future immune challenges.
While trained immunity is well characterized in some cell types, its role in non-immune cells such as epithelium remains understudied.
Respiratory epithelium is a…
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