CORDIS Project
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This project aims to bridge the gap between genomic characterization and predictions of gene expression regulation by using fluorescence reporter techniques and high-throughput genetic manipulations in budding yeast. It focuses on understanding transcriptional responses to osmotic stress and carbon source shifts, ultim…
The precise regulation of gene expression has been the subject of extensive scrutiny.
Nonetheless, there is a big gap between genomic characterization of transcriptional responses and our predictions based on known molecular mechanisms and networks and of transcription regulation.
In this proposal I argue for an approach to bridge this gap by using a novel experimental strategy that exploits the recent maturation of two technologies: the use of fluorescence reporter techniques to monitor promot…
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