CORDIS Project
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This research focuses on the role of transforming growth factor beta (TGFb) in cell growth regulation and cancer progression. It aims to uncover the molecular mechanisms by which TGFb influences transcription and its implications for colorectal cancer.
To understand, treat, cure and ultimately prevent cancer we must first be able to understand the basic mechanisms that regulate normal cell growth.
One of the cellular factors involved both in normal development and in malignant transformation is transforming growth factor b TGFb. TGFb is a multifunctional cytokine which, in addition to cancer is also implicated in developmental disorders, fibrosis and autoimmune diseases. TGFb signalling has been implicated in both tumour suppression and progre…
CANCER RESEARCH UK LBG
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