CORDIS Project
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This project investigates the regulatory roles of small RNAs in bacteria, focusing on their ability to influence gene expression through various mechanisms. By utilizing RNA sequencing technologies, it aims to map how these RNAs interact with target molecules, potentially redefining their role in cellular processes.
Small RNAs (sRNAs) are major regulators of gene expression in bacteria, exerting their regulation in trans by base pairing with target RNAs.
Traditionally, sRNAs were considered post-transcriptional regulators, mainly regulating translation by blocking or exposing the ribosome binding site.
However, accumulating evidence suggest that sRNAs can exploit the base pairing to manipulate their targets in different ways, assisting or interfering with various molecular processes involving the target RNA…
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