CORDIS Project
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This project investigates the evolution of limb regeneration in Axolotls, focusing on the unique expression patterns of limb morphogens during development. It aims to understand how these patterns contribute to regeneration specificity and the molecular basis of positional memory.
Molecular studies of development in diverse animal models have revealed the remarkably conserved set of morphogens governing growth and patterning of body axes and organ fields.
Equally astounding is the diversity of form and function arising from the implementation of these morphogens.
The systematic analysis of well-defined traits in closely related species has revealed how changes in gene regulatory sequences and their trans-acting factors have yielded diversity.
An important future challen…
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