CORDIS Project
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This project explores the biology of cell wall deficient bacteria, known as L-form bacteria, which are resistant to common antibiotics. It aims to understand how these bacteria regenerate their cell walls, which could lead to new treatments for chronic infections and biotechnological applications.
Cell wall deficient (L-form) bacteria are thought to be important in various resistant, persistent or chronic infections. L-form cells are highly abnormal in size and shape and are sensitive to osmotic shock but highly resistant to antibiotics that work on the cell wall (e.g. penicillins and cephalosporins).
How these unusual cells arise and how they proliferate in the absence of a wall, is poorly understood.
The Errington lab recently developed a model system for studying this long standing pro…
UNIVERSITY OF NEWCASTLE UPON TYNE
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