CORDIS Project
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REGENER-OMIX investigates the role of fibroblasts and the microbiome in tissue regeneration and fibrosis. By exploring their interactions, the project aims to develop new strategies to enhance healing and reduce fibrotic tissue formation, which can impact organ function and overall health.
Upon injury or disease, most human organs yield fibrotic tissue resulting in permanent scars and the failure of tissue function, compromising the health span and lifespan of affected individuals.
Organ fibrosis is influenced by a myriad of factors, including fibroblast heterogeneity, the activated signal transduction pathways and environmental cues.
Fibroblasts hold a central role in fibrosis, yet a nuanced understanding of their heterogeneity driving regenerative versus fibrotic healing remains…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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United States, Stanford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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