CORDIS Project
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This project investigates how mechanical and chemical interactions influence the development of tissues, focusing on how noise and variability can contribute to reliable tissue formation. By creating models and conducting experiments, it aims to uncover the mechanisms that ensure robust morphogenesis despite inherent b…
Development involves increasingly intricate processes of physical tissue sculpting (morphogenesis), resulting in highly reproducible shapes.
The apparent paradox between reproducibility at macroscopic scales, and emerging evidence of extensive heterogeneity and stochasticity at the molecular and cellular scales, suggests that active mechanisms are necessary to ensure morphogenetic robustness.
However, as biomechanical theories of morphogenesis have largely ignored the presence and many facets of…
INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
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