CORDIS Project
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This project aims to develop a new method for mapping elemental distribution within biological macromolecules using advanced electron microscopy techniques. The goal is to achieve atomic-resolution elemental mapping to improve our understanding of molecular structures.
A perfect macromolecular structure would provide an all-atom description of the molecule, including not only the well-ordered polypeptide or polynucleotide framework but all other species: metals and other ions, cofactors, lipids, substrates and inhibitors.
However, current structural data include no or very little information on elemental composition, leading to significant errors and omissions in atomic models.
To address this issue, I propose to develop a method, Reconstructed Electron Energy…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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