CORDIS Project
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This project aims to create an in vitro system to study the fission process of transport vesicles in eukaryotic cells. It will investigate the role of specific proteins in membrane dynamics and intracellular transport.
Eukaryotic cells contain a variety of membrane-enclosed compartments that are connected by dynamic transport processes facilitated by vesicles.
The temporal and spatial regulation of these transport processes is essential for cellular function.
After initial formation transport vesicles are separated from their donor membrane and this fission event seems to be coordinated with the elongation of tubular precursors pulled by motor proteins.
Recent results from the host laboratory demonstrated a di…
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