CORDIS Project
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This project investigates human genetic recombination at the single molecule level, focusing on homologous recombination, which is crucial for DNA repair and genome stability. Using advanced imaging techniques, the research aims to analyze the roles of DNA repair proteins in these processes.
The goal of the research is to understand the mechanistic of human genetic recombination at the single molecular level.Homologous recombination, the exchange of sequences between homologous DNA molecules, is essential for accurate genome duplication, DNA damage repair and chromosome segregation.
Single molecule analysis provides information on intermediate states, functional and structural variability and the distribution of variable states that cannot be recovered from bulk biochemical assays.U…
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
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