CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates how the protein UHRF1 interacts with hemi-methylated DNA to facilitate the maintenance of DNA methylation patterns during cell division. It aims to understand the energetic basis of this interaction and the mechanisms involved in flipping methylcytosine, which is crucial for gene regulation an…
Cytosine methylation of CpG dinucleotide sequence is an epigenetic mark on the DNA that regulates gene expression, chromatin structure, and genome stability.
Patterns of DNA methylation propagate with fidelity greater than 99% and their stable inheritance for more than 80 cell divisions.
This robustness is essential as evidenced by the observation that cancer cells commonly exhibit aberrant methylation patterns.
Inheritance and maintenance of methylation patterns are mediated by Dnmt1 during chr…
UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
