CORDIS Project
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This project investigates how small interfering RNAs from tapetal cells regulate gene expression in male meiocytes through a unique DNA methylation process. It aims to understand the mechanisms behind this targeting and its role in plant resilience to heat stress, ultimately contributing to crop improvement strategies.
In flowering plants, DNA methylation reprogramming occurs in meiocytes through RNA-directed DNA methylation pathway (RdDM) mediated by 24-nucleotide small interfering RNAs (siRNAs).
My host lab discovered that these siRNAs are transcribed from transposable element (TE) in tapetal cells (tapetum) and transported to male meiocyte.
In meiocytes, these siRNAs induce methylation at genes (MetGenes) with similar (but not identical) sequences, and thereby regulate MetGene expression and promote meiosis…
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