CORDIS Project
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This project explores transcriptional read-through in bacteria, focusing on its role in gene regulation and genetic networks. By manipulating transcription termination, it aims to understand its effects on bacterial fitness and phenotype.
Control of transcription in bacteria is achieved at many levels, including regulation of transcription initiation and termination, as well as the availability and stability of mRNAs.
While some of these mechanisms have been extensively studied and seem to be tightly controlled, transcription termination is often strikingly inefficient.
Why such a central process should be inefficient is unclear, although in several cases transcriptional read-through has been reported to benefit the cell.
Our aim…
INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
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