CORDIS Project
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This project aims to develop a reliable preclinical model of human testicular tissue to better understand male infertility treatments. By creating a hydrogel that mimics native tissue properties, the project will facilitate high-throughput experimentation and automated analysis to identify effective therapies.
Western society is on the brink of a fertility crisis, whereby human sperm counts have dropped by 59% over the past four decades and are projected to reach zero by 2045.
Treatments for the primary causes of male infertility have no scientific basis, with urologists relying on ineffective empirical medical strategies (guess work).
Identifying effective male fertility treatments requires appropriate preclinical models of the sperm-producing testes that can establish a mechanistic basis for treatme…
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