CORDIS Project
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This project develops a novel optical microscopy technique called Nanofluidic Scattering Microscopy, which allows for the imaging of individual biomolecules in free motion without chemical modifications. By integrating rapid nanofluidic valves, it aims to enhance the study of biomolecular interactions at a single-molec…
A major challenge in biomolecular research is the investigation of biomolecular interaction at single-molecule level.
Biomolecules possess heterogeneities of high physiological relevance that can only be unravelled with single-molecule tools.
All current single-molecule imaging methods, however, require chemical modifications, such as fluorescent labelling or immobilization onto a surface, which might alter the biomolecule’s natural behaviour.Recently, I have developed a ground-breaking optical…
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